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BRCA1 and BRCA2 mutations in Turkish familial and non-familial ovarian cancer patients: a high incidence of mutations in non-familial cases.

Human mutation - 1 Jul 2002

Yazici Hulya, Glendon Gordon, Yazici Hilal, Burnie Steve J, Saip Pánar, Buyru Faruk, Bengisu Ergin, Andrulis Irene L, Dalay Nejat, Ozcelik Hilmi

Abstract excerpt

Ovarian cancer is a clinically important cancer in Turkey. The contribution of BRCA1 and BRCA2 to ovarian cancer in Turkish patients has not previously been described. In this study we investigated the presence of BRCA1 and BRCA2 mutations in 102 consecutively ascertained, hospital-based, ovarian cancer cases. Four out of 15 (26.7%, 95% confidence interval (CI), 7.8%-55.1%) familial cases were found to carry...

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Source

Identifiers

PMID: 12112655
DOI: 10.1002/humu.10090

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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