Molecular cloning and expression during spermatogenesis of a cDNA encoding testicular 11β‐hydroxylase (P450<scp>11β</scp>) in rainbow trout (<i>Oncorhynchus mykiss</i>)

Abstract excerpt

Cytochrome P450 1beta-hydroxylase (P450(11beta)) is an important steroidogenic enzyme for glucocorticoid and mineralocorticoid production in vertebrates. In teleosts, P450(11beta) also plays a role in the production of 11-ketotestosterone (11-KT), the predominant androgen in male fish. In this study, we cloned a cDNA encoding rainbow trout (Oncorhynchus mykiss) testicular P450(11beta). The cDNA contains 1,740...

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