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Functional characterization and expression analysis of the androgen receptor in zebrafish ( <i>Danio rerio</i> ) testis

9 May 2008

Abstract excerpt

The biological activity of androgens, important for male sexual differentiation and development, is mediated by the androgen receptor (AR) that binds to specific DNA recognition sites regulating the transcription of androgen target genes. We investigated androgen production by adult zebrafish testis tissue, and identified 11beta-hydroxyandrostenedione, 11-ketoandrostenedione (OA), and 11-ketotestosterone (11-KT)...

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PMID: 18469035
DOI: 10.1530/rep-08-0055

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