Article
IGF-I is critical for normal vascularization of the human retina.
The Journal of clinical endocrinology and metabolism - 1 Jul 2002
Hellström Ann, Carlsson Björn, Niklasson Aimon, Segnestam Karin, Boguszewski Margaret, de Lacerda Luiz, Savage Martin, Svensson Elisabeth, Smith Lois, Weinberger Dov, Albertsson Wikland Kerstin, Laron Zvi
Abstract excerpt
Experimental and clinical studies suggest that GH and IGF-I may be involved in neovascularization of the retina in diabetes and retinopathy of prematurity. However, the role of GH and IGF-I has not been well established in normal retinal vessel development in humans. Therefore, we examined retinal vessel morphology by digital image analysis of ocular fundus photographs in 13 patients with genetic defects of the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.