Article
Streptogramin antibiotics: mode of action and resistance.
Current drug targets - 1 Aug 2002
Johnston Nicole J, Mukhtar Tariq A, Wright Gerard D
Abstract excerpt
The streptogramin antibiotics were discovered over 40 years ago but are only now emerging as important therapeutic agents for the treatment of infection caused by a variety of bacteria. The streptogramins consist of mixtures of two structurally distinct compounds, type A and type B, which are separately bacteriostatic, but bactericidal in appropriate ratios. These antibiotics act at the level of inhibition of...
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