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[Macrolides, lincosamides, streptogramines (MLS): mechanisms of action and resistance].

Bacteriologia, virusologia, parazitologia, epidemiologia (Bucharest, Romania : 1990) - 1 Jan 2000

Ungureanu Vasilica

Abstract excerpt

Macrolides, lincosamides and streptogramines are distinct antibiotic (AB) families, with different chemical structure, but with similar antibacterial spectre and mechanisms. Macrolides are natural products of secondary metabolism of several species of actynomyces; they represent a group of compounds with a lactonic ring of variable dimensions (12-22 atoms of C) that can bind, by means of glycosidic bonds,...

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PMID: 21553477

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