Prevalence of the Cys282Tyr and His63Asp HFE gene mutations in Spanish patients with hereditary hemochromatosis and in controls.

doi:10.1016/s0168-8278(98)80252-3

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Article

Prevalence of the Cys282Tyr and His63Asp HFE gene mutations in Spanish patients with hereditary hemochromatosis and in controls.

Journal of hepatology - 1 Nov 1998

Sánchez M, Bruguera M, Bosch J, Rodés J, Ballesta F, Oliva R

Abstract excerpt

BACKGROUND/AIMS: A mutation (Cys282Tyr) of the HFE gene has recently been reported to be present in most of the patients with hereditary hemochromatosis of Northern European ancestry, but in a lower frequency in Italy. No data are so far available on the prevalence of these mutations in Spain. Th...

Topics

Adult
Aged
Cysteine
Female
Genes, MHC Class I
HLA Antigens
Hemochromatosis
Hemochromatosis Protein
Histidine
Histocompatibility Antigens Class I
Humans
Male
Membrane Proteins
Middle Aged
Mutation
Spain

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