Article
Wingless blocks bristle formation and morphogenetic furrow progression in the eye through repression of Daughterless.
Development (Cambridge, England) - 1 Jul 2002
Cadigan Kenneth M, Jou Austin D, Nusse Roel
Abstract excerpt
In the developing eye, wingless activity represses proneural gene expression (and thus interommatidial bristle formation) and positions the morphogenetic furrow by blocking its initiation in the dorsal and ventral regions of the presumptive eye. We provide evidence that wingless mediates both effects, at least in part, through repression of the basic helix-loop-helix protein Daughterless. daughterless is required...
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