Article
Positive selection of MHC class Ib-restricted CD8(+) T cells on hematopoietic cells.
Nature immunology - 1 Aug 2002
Urdahl Kevin B, Sun Joseph C, Bevan Michael J
Abstract excerpt
Unlike conventional CD8(+) T cells, major histocompatibility complex (MHC) class Ib-restricted CD8(+) T cells show an activated phenotype in uninfected mice and respond rapidly to foreign invaders. The underlying factors that contribute to these differences are not well understood. We show here that the activated phenotype of MHC class Ib-restricted CD8(+) T cells was partially acquired as a result of...
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