Article
The effects of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 gene on insulin sensitivity and insulin metabolism interact with size at birth.
Diabetes - 1 Jul 2002
Eriksson Johan G, Lindi Virpi, Uusitupa Matti, Forsén Tom J, Laakso Markku, Osmond Clive, Barker David J P
Abstract excerpt
Type 2 diabetes is known to be associated with a small body size at birth. Body size at birth is an indicator of the intrauterine environment. There is also a well-established association between the peroxisome proliferator-activated receptor (PPAR)-gamma2 gene and type 2 diabetes. We therefore assessed whether the effects of the Pro12Ala polymorphism of the PPAR-gamma2 gene on insulin sensitivity and insulin...
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