Article
Apoptosis, onset and maintenance of spermatogenesis: evidence for the involvement of Kit in Kit-haplodeficient mice.
Biology of reproduction - 1 Jul 2002
Guerif Fabrice, Cadoret Veronique, Rahal-Perola Valerie, Lansac Jacques, Bernex Florence, Panthier Jean Jacques, Hochereau-de Reviers Marie Thérèse, Royere Dominique
Abstract excerpt
Kit/stem cell factor (SCF ) has been reported to be involved in survival and proliferation of male differentiating spermatogonial cells. This kinetics study was designed to assess the role of Kit/SCF during spermatogenesis in mice, and the extent of male programmed germ cell death was measured between 8 and 150 days of age. For this purpose, 129/Sv inbred mice in which one Kit allele was inactivated by an nlslacZ...
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