Article
Relation of genetic polymorphisms of apolipoprotein E, angiotensin converting enzyme, apolipoprotein B-100, and glycoprotein IIIa and early-onset coronary heart disease.
Clinical biochemistry - 1 Jun 1999
Nassar B A, Dunn J, Title L M, O'Neill B J, Kirkland S A, Zayed E, Bata I R, Cantrill R C, Johnstone J, Dempsey G I, Tan M H, Breckenridge W C, Johnstone D E
Abstract excerpt
OBJECTIVE: Apolipoprotein E (APOE) E4, apolipoprotein B-100 (APOB) Q3611 allele, the angiotensin converting enzyme (ACE) deletion (D) allele and glycoprotein IIIa (GP3A) P33 mutant allele are reported to predispose to early-onset coronary heart disease (CHD). These associations were not all confirmed in more recent studies. To determine the impact of these alleles on CHD, we examined the prevalence of these...
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