Article
The GP problem: quantifying gene-to-phenotype relationships.
In silico biology - 1 Jan 2002
Cooper Mark, Chapman Scott C, Podlich Dean W, Hammer Graeme L
Abstract excerpt
In this paper we refer to the gene-to-phenotype modeling challenge as the GP problem. Integrating information across levels of organization within a genotype-environment system is a major challenge in computational biology. However, resolving the GP problem is a fundamental requirement if we are to understand and predict phenotypes given knowledge of the genome and model dynamic properties of biological systems....
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