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Article

'Particle genetics': treating every cell as unique.

Trends in genetics : TIG - 1 Feb 2014

Yvert Gaël

Abstract excerpt

Genotype-phenotype relations are usually inferred from a deterministic point of view. For example, quantitative trait loci (QTL), which describe regions of the genome associated with a particular phenotype, are based on a mean trait difference between genotype categories. However, living systems comprise huge numbers of cells (the 'particles' of biology). Each cell can exhibit substantial phenotypic...

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Genetic Association Studies
Genome-Wide Association Study
Genotype
Models, Genetic
Phenotype
Quantitative Trait, Heritable

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Quantitative Trait Loci

Single-Cell Analysis

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Identifiers

PMID: 24315431
DOI: 10.1016/j.tig.2013.11.002
PMCID: PMC4019916

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