Article
'Particle genetics': treating every cell as unique.
Trends in genetics : TIG - 1 Feb 2014
Yvert Gaël
Abstract excerpt
Genotype-phenotype relations are usually inferred from a deterministic point of view. For example, quantitative trait loci (QTL), which describe regions of the genome associated with a particular phenotype, are based on a mean trait difference between genotype categories. However, living systems comprise huge numbers of cells (the 'particles' of biology). Each cell can exhibit substantial phenotypic...
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