Article
Bioinformatics approach to predicting HIV drug resistance.
Expert review of molecular diagnostics - 1 Mar 2006
Cordes Frank, Kaiser Rolf, Selbig Joachim
Abstract excerpt
The emergence of drug resistance remains one of the most challenging issues in the treatment of HIV-1 infection. The extreme replication dynamics of HIV facilitates its escape from the selective pressure exerted by the human immune system and by the applied combination drug therapy. This article reviews computational methods whose combined use can support the design of optimal antiretroviral therapies based on...
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