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Article

Core side-chain packing and backbone conformation in Lpp-56 coiled-coil mutants.

Journal of molecular biology - 3 May 2002

Liu Jie, Cao Wei, Lu Min

Abstract excerpt

Native proteins exhibit precise geometric packing of atoms in their hydrophobic interiors. Nonetheless, controversy remains about the role of core side-chain packing in specifying and stabilizing the folded structures of proteins. Here we investigate the role of core packing in determining the conformation and stability of the Lpp-56 trimerization domain. The X-ray crystal structures of Lpp-56 mutants with...

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Identifiers

PMID: 12054830
DOI: 10.1016/S0022-2836(02)00138-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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