Article
A polymorphism in the interleukin-1alpha gene influences the clinical features of migraine.
Headache - 1 May 2002
Rainero Innocenzo, Pinessi Lorenzo, Salani Giuliana, Valfrè Walter, Rivoiro Chiara, Savi Lidia, Gentile Salvatore, Giudice Rossana Lo, Grimaldi Luigi M E
Abstract excerpt
OBJECTIVE: To evaluate whether a particular genotype of the interleukin-1alpha (IL1A) gene affects the clinical features of migraine. BACKGROUND: Proinflammatory mediators have been reported to play a role in the pathophysiology of migraine. Recent studies suggest that polymorphisms in the interleukin-1 genes influence the age at onset and subsequent course of several chronic inflammatory diseases. METHODS: In a...
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