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Article

Genetic variation in cytokine-related genes and migraine susceptibility.

Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Dec 2013

Stuart Shani, Maher Bridget H, Sutherland Heidi, Benton Miles, Rodriguez Astrid, Lea Rod A, Haupt Larisa M, Griffiths Lyn R

Abstract excerpt

Migraine is classified by the World Health Organization (WHO) as being one of the top 20 most debilitating diseases. According to the neurovascular hypothesis, neuroinflammation may promote the activation and sensitisation of meningeal nociceptors, inducing the persistent throbbing headache characterized in migraine. The tumor necrosis factor (TNF) gene cluster, made up of TNFα, lymphotoxin α (LTA), and...

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Source

Identifiers

PMID: 24054031
DOI: 10.1017/thg.2013.63

Genes

TNF
LTA
LTB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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