Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Distal mdx muscle groups exhibiting up-regulation of utrophin and rescue of dystrophin-associated glycoproteins exemplify a protected phenotype in muscular dystrophy.

Die Naturwissenschaften - 1 Feb 2002

Dowling Paul, Culligan Kevin, Ohlendieck Kay

Abstract excerpt

Unique unaffected skeletal muscle fibres. unlike necrotic torso and limb muscles, may pave the way for a more detailed understanding of the molecular pathogenesis of inherited neuromuscular disorders and help to develop new treatment strategies for muscular dystrophies. The sparing of extraocular muscle in Duchenne muscular dystrophy is mostly attributed to the special protective properties of extremely...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytoskeletal Proteins
Share to Dystrophin

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Inbred mdx

Share to Muscle Fibers, Skeletal

Share to Muscle, Skeletal

Share to Muscular Dystrophy, Animal

Share to Reference Values

Share to Utrophin

Source

Identifiers

PMID: 12046625
DOI: 10.1007/s00114-001-0289-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Distal mdx muscle groups exhibiting up-regulation of utrophin and rescue of dystrophin-associated glycoproteins exemplify a protected phenotype in muscular dystrophy.PMID 12046625Read ↗

Distal muscular dystrophies.Semantic proximity Read ↗

Dystrophin-deficient zebrafish feature aspects of the Duchenne muscular dystrophy pathology.Semantic proximity Read ↗

The sparing of extraocular muscle in dystrophinopathy is lost in mice lacking utrophin and dystrophinSemantic proximity Read ↗

The dystrophin-related protein, utrophin, is expressed on the sarcolemma of regenerating human skeletal muscle fibres in dystrophies and inflammatory myopathiesSemantic proximity Read ↗

Nonvacuolar myopathy in a large family with both late adult onset distal myopathy and severe proximal muscular dystrophy.Semantic proximity Read ↗

Concordant utrophin upregulation in phenotypically discordant DMD/BMD brothers.Semantic proximity Read ↗

The Dystrophin‐Glycoprotein Complex in the Prevention of Muscle DamageSemantic proximity Read ↗

Dystrophin and utrophin: genetic analyses of their role in skeletal muscle.Semantic proximity Read ↗

Lifespan analysis of dystrophic <i>mdx</i> fast-twitch muscle morphology and its impact on contractile functionSemantic proximity Read ↗

Tongue muscle is protected from dystrophic changes in the Duchenne Muscular Dystrophy RatSemantic proximity Read ↗

Animal models of muscular dystrophy – what can they teach us?Semantic proximity Read ↗

Sub-physiological sarcoglycan expression contributes to compensatory muscle protection in mdx miceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.