Article
Nonvacuolar myopathy in a large family with both late adult onset distal myopathy and severe proximal muscular dystrophy.
Journal of the neurological sciences - 1 Dec 1992
Udd B, Rapola J, Nokelainen P, Arikawa E, Somer H
Abstract excerpt
Late adult onset distal myopathies usually show vacuolar degeneration as a characteristic feature in muscle pathology. In this study vacuolar degeneration was not present in 12 patients with late adult onset distal myopathy. All patients were members of a large kindred, with 26 patients showing this new form of distal leg myopathy. Additionally, a severely disabling proximal muscular dystrophy appeared in eight...
Topics
- Adult
- Aged
- Female
- Humans
- Immunohistochemistry
- Male
- Middle Aged
- Muscles
- Muscular Dystrophies
- Neuromuscular Diseases
- Pedigree
- Phenotype