Article
Three N-terminal variants of the AE2 Cl-/HCO3- exchanger are encoded by mRNAs transcribed from alternative promoters.
The Journal of biological chemistry - 29 Mar 1996
Wang Z, Schultheis P J, Shull G E
Abstract excerpt
Multiple AE2 Cl-/HCO3- exchanger mRNAs have been identified in rat. To determine the genetic basis for these mRNAs and whether they encode different variants of the exchanger, we used both rapid amplification of cDNA ends and S1 nuclease protection protocols and examined the organization of the g...
Topics
- Alternative Splicing
- Amino Acid Sequence
- Animals
- Anion Transport Proteins
- Antiporters
- Base Sequence
- Blotting, Northern
- Cloning, Molecular
- DNA Primers
- Exons
- Gastric Mucosa
- Genetic Variation
- Introns
- Membrane Proteins
- Methionine
- Molecular Sequence Data
- Polymerase Chain Reaction
- Promoter Regions, Genetic