Article
No association of vitamin D-binding protein gene polymorphisms in Japanese patients with MS.
Journal of neuroimmunology - 1 Jun 2002
Niino Masaaki, Kikuchi Seiji, Fukazawa Toshiyuki, Yabe Ichiro, Tashiro Kunio
Abstract excerpt
Vitamin D-binding protein (DBP) is known to function as an immunomodulatory factor, as well as the main carrier of vitamin D. We analyzed the frequencies of two polymorphisms (codon 416 and codon 420) in the DBP gene through a case-control study involving 107 Japanese patients with multiple sclerosis (MS) and 109 healthy controls. None of these polymorphisms showed any association with the occurrence of MS....
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