Article
Vitamin D receptor gene polymorphism in multiple sclerosis and the association with HLA class II alleles.
Journal of the neurological sciences - 1 Aug 2000
Niino M, Fukazawa T, Yabe I, Kikuchi S, Sasaki H, Tashiro K
Abstract excerpt
We have previously reported that the association between Bsm I polymorphism, one of the vitamin D receptor genes (VDRG) polymorphism, and multiple sclerosis (MS). In this report, we investigated the further possible role or relevance of VDRG in the pathogenesis of MS. Apa I polymorphism was detected by PCR-RFLP from the DNA of 77 conventional MS patients and 95 healthy controls. The study of the Bsm I and Apa I...
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