[Influence of plasma lipids, APOE genotype and type of LDL receptor gene mutations on myocardial infarction in subjects with familial hypercholesterolemia].

Abstract excerpt

BACKGROUND: Our goal was to analyze the relationship of lipids and lipoproteins, APOE genotype and mutations of the LDL receptor gene with the prevalence of myocardial infarction (MI) in patients with familial hypercholesterolemia (FH) from a Southern European FH population. PATIENTS AND METHOD: We studied 108 heterozygous FH subjects aged > 35 years (41 males). It was a cross-sectional study comparing...

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