Article
Differences in characteristics and risk of cardiovascular disease in familial hypercholesterolemia patients with and without tendon xanthomas: a systematic review and meta-analysis.
Atherosclerosis - 1 Dec 2009
Oosterveer Daniëlla M, Versmissen Jorie, Yazdanpanah Mojgan, Hamza Taye H, Sijbrands Eric J G
Abstract excerpt
BACKGROUND: Tendon xanthomas are characteristic of familial hypercholesterolemia (FH). It is not clear whether FH patients with xanthomas have higher risk of cardiovascular disease (CVD) than those without xanthomas. The clinical diagnosis of FH in patients without xanthomas, namely requires the presence of CVD in the patient or in a first-degree relative. This may have masked the association between xanthomas...
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