Article
[Familial hypercholesterolemia: A largely underestimated cardiovascular risk].
Annales de cardiologie et d'angeiologie - 1 Feb 2018
Ferrières J, Bruckert É, Béliard S, Rabès J-P, Farnier M, Krempf M, Cariou B, Danchin N
Abstract excerpt
BACKGROUND: Familial hypercholesterolemia is a monogenic autosomal dominant dyslipidemia characterized by a permanent and isolated increase of cholesterol carried by low-density lipoproteins. The prevalence of its heterozygous form is estimated between 1/500 and 1/250, and in the absence of specific treatment, this form is responsible for an increase by a factor of 13 of the risk of premature coronary artery...
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