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Article

Linking quorum sensing regulation and biofilm formation by Candida albicans.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011

Deveau Aurélie, Hogan Deborah A

Abstract excerpt

Candida albicans biofilms are surface-associated, structured communities composed of yeast, hyphal, and pseudohyphal cells surrounded by an extracellular matrix. C. albicans biofilms often lead to life-threatening systemic infections and are particularly difficult to eradicate because of their high levels of resistance to antibiotics. Farnesol, an autoregulatory molecule secreted by C. albicans, inhibits hyphal...

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PMID: 21031315
DOI: 10.1007/978-1-60761-971-0_16

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