Article
The human sideroflexin 5 (SFXN5) gene: sequence, expression analysis and exclusion as a candidate for PARK3.
Gene - 20 Feb 2002
Lockhart Paul J, Holtom Benjamin, Lincoln Sarah, Hussey Jennifer, Zimprich Alexander, Gasser Thomas, Wszolek Zbigniew K, Hardy John, Farrer Matthew J
Abstract excerpt
Parkinson's disease (PD) is a common neurodegenerative disorder with clinical features of bradykinesia, rigidity and resting tremor resulting from the deficiency of dopamine in the nigrostriatal system. Previously we mapped a susceptibility gene for an autosomal dominant form of PD to a 10.6 cM region of chromosome 2p (PARK3; OMIM 602404). Here we report the identification and characterization of the human...
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