Article
A W-linked DM-domain gene, DM-W, participates in primary ovary development in Xenopus laevis.
Proceedings of the National Academy of Sciences of the United States of America - 19 Feb 2008
Yoshimoto Shin, Okada Ema, Umemoto Hirohito, Tamura Kei, Uno Yoshinobu, Nishida-Umehara Chizuko, Matsuda Yoichi, Takamatsu Nobuhiko, Shiba Tadayoshi, Ito Michihiko
Abstract excerpt
In the XX/XY sex-determining system, the Y-linked SRY genes of most mammals and the DMY/Dmrt1bY genes of the teleost fish medaka have been characterized as sex-determining genes that trigger formation of the testis. However, the molecular mechanism of the ZZ/ZW-type system in vertebrates, including the clawed frog Xenopus laevis, is unknown. Here, we isolated an X. laevis female genome-specific DM-domain gene,...
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