Article
Expression levels of apoptosis-related proteins predict clinical outcome in anaplastic large cell lymphoma
15 Jun 2002
Abstract excerpt
In vitro studies suggest that resistance to chemotherapy-induced apoptosis might explain poor response to therapy in fatal cases. Actual execution of apoptosis depends on proper functioning of effector caspases, particularly caspase 3, and on the expression levels of apoptosis-regulating proteins, including Bcl-2 and the recently identified granzyme B- specific protease inhibitor 9 (PI9). Thus, high levels of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
