Article
Characterization of the T-cell response to coxsackievirus B4: evidence that effector memory cells predominate in patients with type 1 diabetes.
Diabetes - 1 Jun 2002
Varela-Calvino Ruben, Ellis Richard, Sgarbi Gianluca, Dayan Colin M, Peakman Mark
Abstract excerpt
Most of the evidence linking enterovirus (EV) infection with the development and/or acceleration of type 1 diabetes is indirect. Few studies have examined T-cell responses to these viruses, and therefore the nature of the viral targets and the immune cells involved in antiviral responses remain unclear. In the present study, we examined the characteristics of the T-cell response to the EV Coxsackievirus B4 (CVB4)...
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