Article
Diversity of complement factor B/C2 in the common carp (Cyprinus carpio): three isotypes of B/C2-A expressed in different tissues.
Developmental and comparative immunology - 1 Jul 2002
Nakao Miki, Matsumoto Momoe, Nakazawa Mika, Fujiki Kazuhiro, Yano Tomoki
Abstract excerpt
Complement factor B and C2 are two critical proteases for complement activation. Some bony fish have been reported to possess duplicated genes for B/C2, but there is no direct evidence regarding possible functional divergence. Here, we report the isolation of the second and third isotypes of carp B/C2-A, a close relative of other bony fish B reported to date, and designated B/C2-A2 and B/C2-A3. B/C2-A1...
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