Article
Molecular cloning of the complement (C1r/C1s/MASP2-like serine proteases from the common carp (Cyprinus carpio).
Immunogenetics - 1 Jan 2001
Nakao M, Osaka K, Kato Y, Fujiki K, Yano T
Abstract excerpt
The classical pathway of complement composed of C1, C4, and C2 is an antibody-dependent activation cascade that is present in jawed vertebrates. C1 is a Ca2+-dependent complex of C1q, C1r, and C1s, and analogous to an initiation complex of the lectin pathway of complement, which consists of the m...
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