Article
Hormone-specific regulation of the kidney androgen-regulated gene promoter in cultured mouse renal proximal-tubule cells.
The Biochemical journal - 15 Sept 2002
Soler Montse, Tornavaca Olga, Solé Esther, Menoyo Anna, Hardy Dianne, Catterall James F, Vandewalle Alain, Meseguer Anna
Abstract excerpt
The kidney androgen-regulated protein (KAP) is specifically expressed and differentially regulated by androgens and tri-iodothyronine (T(3)) in intact mouse early (PCT) and late (PR) proximal-tubule cells. Until now, detailed characterization of the molecular elements mediating androgen-responsive gene expression in the kidney has been hampered by the lack of appropriate cultured cell systems suitable for DNA...
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