Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quantitative analysis of a MDR1 transcript for prediction of drug resistance in acute leukemia.

Clinical chemistry - 1 Jun 2002

Fujimaki Shin-ichi, Funato Tadao, Harigae Hideo, Fujiwara Junko, Kameoka Junichi, Meguro Kuniaki, Kaku Mitsuo, Sasaki Takeshi

Abstract excerpt

BACKGROUND: Assessing the drug resistance of leukemic cells is important for treatment of leukemia. We developed a quantitative reverse transcription (RT)-PCR method for multidrug resistance 1 (MDR1) and multidrug resistance-related protein 1 (MRP1) transcripts to evaluate drug resistance, and applied it to clinical samples. METHODS: The cutoffs for copy numbers of MDR1 and MRP1 transcripts were defined based on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP Binding Cassette Transporter, Subfamily B, Member 1
Share to Drug Resistance, Multiple

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Resistance, Neoplasm

Share to Drug Screening Assays, Antitumor

Share to Leukemia, Myeloid, Acute

Share to Multidrug Resistance-Associated Proteins

Share to Neoplasm Recurrence, Local

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Source

Identifiers

PMID: 12028995

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quantitative analysis of a MDR1 transcript for prediction of drug resistance in acute leukemia.PMID 12028995Read ↗

Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction.Semantic proximity Read ↗

Multidrug resistance in leukemiaSemantic proximity Read ↗

Multidrug resistance (mdr1) gene expression in adult acute leukemias: correlations with treatment outcome and in vitro drug sensitivitySemantic proximity Read ↗

Classical multidrug resistance in acute myeloid leukaemia.Semantic proximity Read ↗

Functional multidrug resistance phenotype associated with combined overexpression of Pgp/MDR1 and MRP together with 1-beta-D-arabinofuranosylcytosine sensitivity may predict clinical response in acute myeloid leukemia.Semantic proximity Read ↗

Advances in the Molecular Detection of ABC Transporters Involved in Multidrug Resistance in CancerSemantic proximity Read ↗

MRP1 polymorphisms (T2684C, C2007T, C2012T, and C2665T) are not associated with multidrug resistance in leukemic patients.Semantic proximity Read ↗

Prognostic Significance of Multidrug Resistance Gene 1 (MDR1), Multidrug Resistance-related Protein (MRP) and Lung Resistance Protein (LRP) mRNA Expression in Acute LeukemiaSemantic proximity Read ↗

Multiple drug resistance protein (MDR-1), multidrug resistance-related protein (MRP) and lung resistance protein (LRP) gene expression in childhood acute lymphoblastic leukemiaSemantic proximity Read ↗

Characterization of a multidrug-resistant chronic myeloid leukemia cell line presenting multiple resistance mechanisms.Semantic proximity Read ↗

Expression of Multidrug Resistance 1 (MDR1), Multidrug Resistance-Related Protein 1 (MRP1), Lung Resistance Protein (LRP), and Breast Cancer Resistance Protein (BCRP) Genes and Clinical Outcome in Childhood Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

Multidrug resistance in acute myeloid leukaemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.