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Article

The role of constant region carbohydrate in the assembly and secretion of human IgD and IgA1.

The Journal of biological chemistry - 9 Aug 2002

Gala Francoise A, Morrison Sherie L

Abstract excerpt

Immunoglobulins are glycoproteins, containing N- linked carbohydrates in the heavy chain constant regions of all isotypes and O-linked carbohydrates in the hinge regions of human IgA1 and IgD. A previous study showed that IgD synthesized in the presence of tunicamycin and lacking the three N-linked glycans on the heavy chain was not secreted (Shin, S. U., Wei, D. F., Amin, A. R., Thorbecke, G. J., and Morrison,...

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Identifiers

PMID: 12023968
DOI: 10.1074/jbc.M203258200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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