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Article

Bone resorption in chronic otitis media: the role of the osteoclast.

ORL; journal for oto-rhino-laryngology and its related specialties - 1 Jan 2000

Jung Jae Y, Chole Richard A

Abstract excerpt

Most of the pathology associated with cholesteatoma is the result of osteoclast-mediated bone resorption in the middle ear. Cytokines, prostaglandins, nitric oxide, neurotransmitters and growth factors are associated with chronic inflammation and have been implicated in cholesteatoma-induced bone resorption. Although many different factors are known to regulate osteoclast activation, there is a final common...

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Identifiers

PMID: 12021500
DOI: 10.1159/000057787

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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