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Article

Association of Grb7 with phosphoinositides and its role in the regulation of cell migration.

The Journal of biological chemistry - 9 Aug 2002

Shen Tang-Long, Han Dong Cho, Guan Jun-Lin

Abstract excerpt

Grb7 is the prototype of a family of adaptor molecules that also include Grb10 and Grb14 that share a conserved molecular architecture including Src homology 2 (SH2) and pleckstrin homology (PH) domains. Grb7 has been implicated as a downstream mediator of integrin-FAK signal pathways in the regulation of cell migration, although the molecular mechanisms are still not well understood. In this paper, we...

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Source

Identifiers

PMID: 12021278
DOI: 10.1074/jbc.M203085200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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