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Article

Germline mutation of ARF in a melanoma kindred.

Human molecular genetics - 15 May 2002

Hewitt Chelsee, Lee Wu Chu, Evans Gareth, Howell A, Elles Robert G, Jordan Richard, Sloan Philip, Read Andrew P, Thakker Nalin

Abstract excerpt

Familial melanoma predisposition is associated with germline mutations at the CDKN2A/ARF locus in up to 40% of families. The exact role of the two proteins encoded by this complex locus in this predisposition is unclear. Most mutations affect either CDKN2A only or products of both genes. Recently...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12019208
DOI: 10.1093/hmg/11.11.1273

Genes

FAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12019208-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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