Article
Androgen receptor phosphorylation. Regulation and identification of the phosphorylation sites.
The Journal of biological chemistry - 9 Aug 2002
Gioeli Daniel, Ficarro Scott B, Kwiek Jesse J, Aaronson David, Hancock Mathew, Catling Andrew D, White Forest M, Christian Robert E, Settlage Robert E, Shabanowitz Jeffrey, Hunt Donald F, Weber Michael J
Abstract excerpt
Activation of signal transduction kinase cascades has been shown to alter androgen receptor (AR) activity. Although it has been suggested that changes in AR phosphorylation might be directly responsible, the basal and regulated phosphorylations of the AR have not been fully determined. We have identified the major sites of AR phosphorylation on ARs expressed in COS-1 cells using a combination of peptide mapping,...
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