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Regulation of the Overlapping pic/set Locus in Shigella flexneri and Enteroaggregative Escherichia coli

1 Jun 2002

Abstract excerpt

Most strains of Shigella flexneri 2a and enteroaggregative Escherichia coli carry a highly conserved chromosomal locus which encodes a 109-kDa secreted mucinase (called Pic) and, on the opposite strand in overlapping fashion, an oligomeric enterotoxin called ShET1, encoded by the setA and setB genes. Here, we characterize the genetic regulation of these overlapping genes. Our data suggest that pic and the setBA...

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PMID: 12010980
DOI: 10.1128/iai.70.6.2915-2925.2002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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