Article
Insertion/Deletion polymorphism of Angiotensin-converting enzyme as a risk factor for chronic allograft nephropathy.
Transplantation proceedings - 1 Jan 2000
Fedor R, Asztalos L, Löcsey L, Szabó L, Mányiné I S, Fagyas M, Lizanecz E, Tóth A
Abstract excerpt
Angiotensin-converting enzyme (ACE) inhibitor therapy is widely used to treat chronic allograft nephropathy (CAN), which suggests a possible role of the renin-angiotensin system in the pathologic mechanism of the disease. The objective of this study was to investigate the possible link between CAN and ACE. The ACE insertion/deletion polymorphism and the amount and activity of ACE were determined in cadaver kidney...
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