Article
Vitamin D Receptor Gene Polymorphisms Influence T1D Susceptibility among Pakistanis
1 Jan 2017
Abstract excerpt
Background. The vitamin D receptor (VDR) gene regulates insulin secretion from the pancreas and acts as a mediator of the immune response through vitamin D. Polymorphism in VDR causes alterations in the functioning of vitamin D, leading to type 1 diabetes (T1D) predisposition. The aim of the present study was to determine VDR gene polymorphism in association with T1D in Pakistanis. Methods. The association was...
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