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Article

The ARO4 gene of Candida albicans encodes a tyrosine-sensitive DAHP synthase: evolution, functional conservation and phenotype of Aro3p-, Aro4p-deficient mutants.

Microbiology (Reading, England) - 1 May 2002

Sousa Silvino, McLaughlin Megan M, Pereira Sarita A, VanHorn Stephanie, Knowlton Robert, Brown James R, Nicholas Richard O, Livi George P

Abstract excerpt

The enzyme 3-deoxy-D-arabinoheptulosonate-7-phosphate (DAHP) synthase catalyses the first step in aromatic amino acid biosynthesis in prokaryotes, plants and fungi. Cells of Saccharomyces cerevisiae contain two catalytically redundant DAHP synthases, encoded by the genes ARO3 and ARO4, whose activities are feedback-inhibited by phenylalanine and tyrosine, respectively. ARO3/4 gene transcription is controlled by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 11988503
DOI: 10.1099/00221287-148-5-1291

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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