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Article

The role of mutations affecting gonadotrophin secretion and action in disorders of pubertal development.

Best practice & research. Clinical endocrinology & metabolism - 1 Mar 2002

Huhtaniemi Ilpo T

Abstract excerpt

A number of mutations that disturb the development and function of the hypothalamic-pituitary-gonadal (HPG) axis and cause disturbances in pubertal development are known today. These mutations have effects at all levels of the HPG axis, from the migration of gonadotrophin releasing hormone (GnRH) neurones from the nasal cavity to the hypothalamus, GnRH secretion, GnRH action, pituitary gonadotroph...

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Identifiers

PMID: 11987903
DOI: 10.1053/beem.2002.0185

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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