Article
Mutations along the hypothalamic-pituitary-gonadal axis affecting male reproduction.
Reproductive biomedicine online - 1 Dec 2007
Huhtaniemi Ilpo, Alevizaki Maria
Abstract excerpt
Disorders in male reproductive function are caused by mutations of key genes at all levels of the hypothalamic-pituitary- testicular axis. They may affect the ontogeny and function of the hypothalamic centres governing gonadotrophin synthesis and secretion, the development of the anterior pituitary gland, the production of gonadotrophins and the function of their receptor genes, and finally the genes responsible...
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