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Congenital Hypogonadotropic Hypogonadism and Kallmann Syndrome: Past, Present, and Future

1 Jan 2015

Abstract excerpt

The proper development and coordination of the hypothalamic-pituitary-gonadal (HPG) axis are essential for normal reproductive competence. The key factor that regulates the function of the HPG axis is gonadotrophin-releasing hormone (GnRH). Timely release of GnRH is critical for the onset of puberty and subsequent sexual maturation. Misregulation in this system can result in delayed or absent puberty and...

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PMID: 26790381
DOI: 10.3803/enm.2015.30.4.456

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