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Article

Silencing of pi-class glutathione S-transferase in MDA PCa 2a and MDA PCa 2b cells.

The Prostate - 1 Jun 2002

Vidanes Genevieve M, Paton Vince, Wallen Eric, Peehl Donna M, Navone Nora, Brooks James D

Abstract excerpt

BACKGROUND: Loss of expression of the glutathione S-transferase-pi (GSTP1) is the most common genetic alteration described in human prostate cancer, occurring in virtually all tumors regardless of grade or stage. Of the available human prostate cancer cell lines, only LNCaP mirrors this phenotype. We investigated whether the prostate cancer cell lines MDA PCa 2a and MDA PCa 2b share this phenotype. METHODS: GSTP1...

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Share to DNA Methylation
Share to DNA, Neoplasm
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glutathione S-Transferase pi

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Source

Identifiers

PMID: 11987150
DOI: 10.1002/pros.10093

Genes

GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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