Article
Glutathione S-transferase pi gene methylation: the search for a molecular marker of prostatic adenocarcinoma.
Advances in anatomic pathology - 1 Nov 2000
Jimenez R E, Fischer A H, Petros J A, Amin M B
Abstract excerpt
Glutathione S-transferase pi gene methylation has recently been described in prostatic adenocarcinoma. Aggregate data on 115 samples studied to date have found an 87% sensitivity and 92% specificity for prostate cancer diagnosis. The current literature about this new marker is herein summarized, and possible molecular mechanisms by which glutathione S-transferase pi may participate in prostatic carcinogenesis are...
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