Article
Pancreatic cancer: current understanding of molecular and genetic aetiologies.
Postgraduate medical journal - 1 Oct 2015
Gall Tamara M H, Wasan Harpreet, Jiao Long R
Abstract excerpt
Pancreatic ductal adenocarcinoma (PDAC) is one of the few cancers where prognosis has not improved over the past few decades. However, there have been several advances in our understanding of the disease leading to earlier detection and targeted therapeutic treatment. It is now understood that specific somatic and germline mutations lead to the development of the disease, and the risk factors associated with this...
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